Use of a Lab-8 computer for on-line analysis of force-velocity characteristics of skeletal muscle

✍ Scribed by K.W Ranatunga

• Publisher: Elsevier Science
• Year: 1972
• Weight: 274 KB
• Volume: 2
• Category: Article
• ISSN: 0010-468X
• DOI: 10.1016/0010-468x(72)90041-4

✦ Synopsis

A software system, ISOT, has been developed to use a Lab-8 computer for on-line recording of isotonic contractions and analysis of force/velocity characteristics of skeletal muscle. The basic lay-out of the programme is essen-tiaUy similar to ISOM.

During each cycle the muscle is stimulated and the output from the displacement transducer, to which the muscle is attached, is sampled at a preset rate. These samples are displayed along a calibrated time base. ISOT computes the slope of a user defined section of this signal and represents it as the velocity of shortening. The velocity (V) and other characteristics such as temperature (TM), frequency (FQ), and duration (DN) of stimulation and load (= force, P) against which the muscle shortened are obtainable as an alphanumeric CRO display and/or a teletype printout during each cycle.

In further analyses of these results ISOT assumes that the relationship between the force (P) and the velocity of shortening (V) of a muscle obeys the equation proposed by A.V. Hill, i.e.,

where a and b are constants, and Po is the maximum isometric force. Using the values for P and V, ISOT computes the constants a and b while the experiment is actually in progress.

A short communication on ISOT has previously been published.

On-line recording and analysis Small computer Force-velocity characteristics of skeletal muscle