Novel svntheses of bromohydrazones and ketoximes could be realized b.y reactions of 3-a-bromoacetylcoumarin with n variety of reagents. Such compounds reacted readily with nucleophiles to give unique heterocyclic systenis.
Use of 3–(2′-formyl-1′-chlorovinyl)coumarin in the syntheses of pyrazol, salicylaldazine and pyrimidine derivatives
✍ Scribed by Ibrahim M. El-Deen
- Book ID
- 102098579
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 347 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0256-7660
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✦ Synopsis
Faculty of,!?&cabn, Suez Canal UniYmity , Port-Said, Egypt Absh.act 3-(F'yraml-S-yl)cod (3) was prepand fmm condensation of 3-(2'-formyl-l'-chlo10vinyl)-cOumarin (1) with hydmzine hydrate at mom temperature, followed by cychtion with base. Salicylaldazine was prepared fmrn methoxylation of 1 to give a c e d 7, followed by condensation of 7 with hydrazine hydrate at 809:. Treatment of aced 7 with thiourea yielded the componding 4 -s u b s t i t u t e d -2 -t 2 ~-p ~~n e [ 3,4-b]d n (U) . Keywod Syntheses, pyraml, pyrimidine derivatives
As an extension of our previous w o k , this paper reported the preparation of some heterocyclic compounds containing coumarin moiety and salicylaldazine using 3-( 2'-formy1-l'-chlorovinyl) coumarin
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