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Use-dependent blockade of Cav2.2 voltage-gated calcium channels for neuropathic pain

✍ Scribed by Raymond J. Winquist; Jennifer Qian Pan; Valentin K. Gribkoff

Book ID
113487611
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
321 KB
Volume
70
Category
Article
ISSN
0006-2952

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Voltage-gated calcium channels (VGCC) play obligatory roles in diverse physiological functions. Pathological conditions leading to changes in their biophysical properties and expression levels may cause malfunctions of VGCC-mediated activities, resulting in disease states. It is believed that change