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Ursolic acid induces apoptosis of SW480 cells via p53 activation

✍ Scribed by Nam, Hyang; Kim, Moon-Moo


Book ID
122560259
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
997 KB
Volume
62
Category
Article
ISSN
0278-6915

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## Abstract Ursolic acid (UA), a pentacyclic triterpenoid compound, has been demonstrated to have an antiproliferative effect in various tumors. We investigated the cell killing effects of UA in the human hormone refractory prostate cancer cell line, PC‐3 cells. Also, the molecular mechanisms under