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Ursodeoxycholic acid and primary biliary cirrhosis with features of autoimmune hepatitis

✍ Scribed by Olivier Chazouillères; Raoul Poupon

Book ID
111721935
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
52 KB
Volume
36
Category
Article
ISSN
0270-9139

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BackgroundlAims: A double-blind, placebo-controlled trial of ursodeoxycholic acid (UDCA) was conducted in 180 patients with primary biliary cirrhosis (PBC) to define the efficacy and safety of UDCA Efficacy was assessed by time to treatment failure defined as death; liver transplantation; histologic

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Bile acid composition in fasting duodenal bile was assessed at entry and at 2 years in patients with primary biliary cirrhosis (PBC) enrolled in a randomized, doubleblind, placebo-controlled trial of ursodeoxycholic acid (UDCA) (10-12 mg/kg/d) taken as a single bedtime dose. Specimens were analyzed