Ursodeoxycholic Acid and In Vitro Vasoactivity of Hydrophobic Bile Acids
โ Scribed by Arieh Bomzon; Predrag Ljubuncic
- Book ID
- 110293161
- Publisher
- Springer US
- Year
- 2001
- Tongue
- English
- Weight
- 142 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0163-2116
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๐ SIMILAR VOLUMES
In five patients with radiolucent gallstones, the effect of ursodeoxycholic acid (Urso) in doses of 250,500, 750, 1,000, and 1,250 mg per day on biliary lipid and bile acid composition was studied. Biliary cholesterol decreased from 8.8 f 0.8 mole% to 4.4 f 0.2 mole% at 500 mg Urso per day (7.1 mg p
Bile acid composition in fasting duodenal bile was assessed at entry and at 2 years in patients with primary biliary cirrhosis (PBC) enrolled in a randomized, doubleblind, placebo-controlled trial of ursodeoxycholic acid (UDCA) (10-12 mg/kg/d) taken as a single bedtime dose. Specimens were analyzed
Beneficial effects of ursodeoxycholic acid in chronic cholestatic liver diseases have been attributed to displacement of hydrophobic bile acids from the endogenous bile acid pool. To test this hypothesis, we determined pool sizes, fractional turnover rates, synthesis/input rates and serum levels of