Ursodeoxycholic acid action on the transport function of the small intestine in normal and cystic fibrosis mice
β Scribed by J. Hardcastle; P. T. Hardcastle; J. Chapman; C. J. Taylor
- Book ID
- 111768776
- Publisher
- Pharmaceutical Press
- Year
- 2001
- Tongue
- English
- Weight
- 229 KB
- Volume
- 53
- Category
- Article
- ISSN
- 2042-7158
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Effect of ursodeoxycholic acid (UDCA) treatment on the expression and function of intestinal multidrug resistance-associated protein (Mrp) 2 was examined in rats. When rats were orally administered 0.5% UDCA solution for 6 days, mRNA and protein levels of Mrp2 in the intestine were increased about t
The efficacy of 2 years of treatment with ursodeoxycholic acid (UDCA) in cystic fibrosis (CF)-associated liver disease was evaluated by liver biopsies and liver function tests in 10 patients aged 8 to 28 years. The metabolism of UDCA was investigated by analysis of urinary bile acids with fast atom