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Urothelial carcinomas arising in arsenic-contaminated areas are associated with hypermethylation of the gene promoter of the death-associated protein kinase

✍ Scribed by W-T Chen; W-C Hung; W-Y Kang; Y-C Huang; C-Y Chai

Book ID
110092685
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
385 KB
Volume
51
Category
Article
ISSN
0309-0167

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## Communicated by Stephen Chanock Matrix metalloproteinases (MMPs) play important roles in cancer initiation and development. Several polymorphisms in the promoters of a number of MMP genes, which can affect the respective MMP production in an allele-specific manner, have been well characterized.