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Urotensin II-induced endothelin-1 expression and cell proliferation via epidermal growth factor receptor transactivation in rat aortic smooth muscle cells

✍ Scribed by Chien-Sung Tsai; Shih-Hurng Loh; Ju-Chi Liu; Jia-Wei Lin; Yen-Ling Chen; Cheng-Hsien Chen; Tzu-Hurng Cheng


Book ID
118422475
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
965 KB
Volume
206
Category
Article
ISSN
0021-9150

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## Abstract Insulin is known to cause an increase in endothelin‐1 (ET‐1) receptors in vascular smooth muscle cells (SMCs), but the effect of insulin‐like growth factor 1 (IGF‐1) on ET‐1 receptor expression is not known. We therefore carried out the present study to determine the effect of IGF‐1 on