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Urokinase receptor and colorectal cancer survival

โœ Scribed by SJam Ganesh; CornelisF.M Sier; MartineM Heerding; Gerrit Griffioen; CornelisB.H.W Lamers; HeinW Verspaget


Book ID
118555358
Publisher
The Lancet
Year
1994
Tongue
English
Weight
262 KB
Volume
344
Category
Article
ISSN
0140-6736

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Urokinase plasminogen activator (uPA) is a serine protease involved in cancer invasion and metastasis. uPA mediates its action while attached to a membrane-bound receptor (uPAR). In this investigation we show that uPAR levels correlate with uPA levels in human breast cancers. uPAR levels, however, d