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Urokinase plasminogen activator promotes keratinocyte proliferation in vivo

โœ Scribed by Jensen, P.J.; Carmeliet, P.; Collen, D.; Lavker, R.M.

Book ID
119561900
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
180 KB
Volume
16
Category
Article
ISSN
0923-1811

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Urokinase plasminogen activator (uPA) is a serine protease involved in cancer invasion and metastasis. uPA mediates its action while attached to a membrane-bound receptor (uPAR). In this investigation we show that uPAR levels correlate with uPA levels in human breast cancers. uPAR levels, however, d