Urokinase plasminogen activator induces smooth muscle cell migration: key role of growth factor-like domain
β Scribed by Victoria Stepanova; Alex Bobik; Robert Bibilashvily; Anatoly Belogurov; Igor Rybalkin; Sergey Domogatsky; Peter J. Little; Elena Goncharova; Vsevolod Tkachuk
- Book ID
- 117108091
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 398 KB
- Volume
- 414
- Category
- Article
- ISSN
- 0014-5793
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Urokinaseβtype plasminogen activator (uPA) binds to its receptor, uPAR, on the surface of cancer cells, leading to the formation of plasmin. Rhabdomyosarcoma (RMS) cell lines secrete high levels of insulinβlike growth factor II (IGFβII), suggesting autocrine IGFs play a major role in th
## Abstract The dependence of urokinaseβtype plasminogen activator (uPA) induction on endogenous basic fibroblast growth factor (bFGF) activity during endothelial cell migration was investigated utilizing a combination of wounded endothelial cell monolayers and substrate overlay techniques. Purifie