## Abstract Historically, breast cancer rates have been low in Asia but rates have increased substantially in Asian–Americans for reasons that are not well understood. The authors conducted a population‐based case–control study of breast cancer in Los Angeles County, which included 1,277 (450 Chine
Urine œstrogen profiles OF Asian and North American women
✍ Scribed by Brian MacMahon; Philip Cole; James B. Brown; Kunio Aoki; Tong Ming Lin; Robert W. Morgan; Ngai-Chen Woo
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- French
- Weight
- 428 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Œstrone (El), œstradiol (E2) and œstriol (E3) were measured in the urine of Asian and North American women aged 15‐19, 20‐24 and 30‐39 years, during the follicular and luteal phases of the menstrual cycle. Each urine specimen was characterized by its œstriol proportion, E3/(E1+E2+E3). In each age group and cycle phase Asians had lower concentrations of œstrone and œstradiol and a higher oestriol proportion than North Americans. The differences were greatest in the youngest age group. Differences between the women from two North American cities or between women from three Asian areas were small. The data support the idea that the œstriol proportion, especially among young women, is a correlate of subsequent breast cancer risk.
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