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Urine Metabolite Analysis Offers Potential Early Diagnosis of Ovarian and Breast Cancers

โœ Scribed by Slupsky, C. M.; Steed, H.; Wells, T. H.; Dabbs, K.; Schepansky, A.; Capstick, V.; Faught, W.; Sawyer, M. B.

Book ID
121812447
Publisher
American Association for Cancer Research
Year
2010
Tongue
English
Weight
494 KB
Volume
16
Category
Article
ISSN
1078-0432

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Here we report the study on BRCA1 and BRCA2 mutations in 12 Thai breast and/or ovarian cancer families and 6 early-onset breast or breast/ovarian cancer cases without a family history of cancer. Five distinct rare alterations were identified in each gene: four introducing premature stop codons, one