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Urinary type IV collagen as a marker for early diabetic nephropathy

✍ Scribed by Seijiro Kado; Akira Aoki; Seiki Wada; Yasuyuki Katayama; Nobuo Kugai; Nobuyuki Yoshizawa; Naokazu Nagata


Book ID
116109321
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
504 KB
Volume
31
Category
Article
ISSN
0168-8227

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Type IV collagen is a major component released from the glomerular and tubular basement membranes. To investigate the alteration of renal type IV collagen turnover in early stage diabetic nephropathy, urinary type IV collagen was measured by a highly sensitive one-step sandwich enzyme immunoassay (E

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## Abstract To investigate the changes of renal type IV collagen turnover in diabetic nephropathy, urinary type IV collagen was measured by a highly sensitive one‐step sandwich enzyme immunoassay (EIA). Urinary samples were obtained from 698 diabetic patients and 191 healthy adults. Among the patie