Urinary symptoms and urodynamic findings in patients with Machado–Joseph disease
✍ Scribed by André F. A. Musegante; Priscila N. S. Almeida; André L. Barboza; Ubirajara Barroso
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 380 KB
- Volume
- 258
- Category
- Article
- ISSN
- 0340-5354
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📜 SIMILAR VOLUMES
Machado-Joseph disease (MJD) is a neurodegenerative disorder with auto-soma1 dominant inheritance. We have carried out electrophysiological studies in 8 individuals belonging to a Danish family with several affected members. Five had an expanded trinucleotide (CAG) repeat sequence in the MJDl gene o
## Abstract Although ataxia is the most distressing manifestation of Machado‐Joseph disease (MJD), little is known about its natural history. Therefore, we prospectively followed a cohort of patients with MJD for 13 months to characterize the progression of ataxia and identify its contributory fact