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Urinary excretion of silica in humans following oral administration of Magnesium Trisilicate

✍ Scribed by Reid R. Heffner; Robert C. Page; Andrew Frey

Book ID
112968573
Publisher
Springer-Verlag
Year
1941
Weight
346 KB
Volume
8
Category
Article
ISSN
0002-9211

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The pharmacokinetic disposition of methazolamide (MTZ) was studied in five healthy volunteers following administration of a single oral dose. Drug concentrations in blood, plasma, and urine were measured by HPLC. Over the range of plasma concentrations observed in vivo, MTZ free fraction (measured b