Urinary excretion of endothelin-1 in normal subjects and patients with renal disease
β Scribed by Ohta, Kazuki; Hirata, Yukio; Shichiri, Masayoshi; Kanno, Kazuo; Emori, Toshiaki; Tomita, Kimio; Marumo, Fumiaki
- Book ID
- 109881933
- Publisher
- Nature Publishing Group
- Year
- 1991
- Tongue
- English
- Weight
- 351 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0085-2538
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## Abstract The complex pathogenesis of chronic renal disease (CRD) depends on endothelin (ET) axis (ETs and ET receptors) and nitric oxide (NO) because of their vasoactive effects and their role in general modulation of vascular homeostasis. Various renal cells synthesize ETs and NO that play a si
Using an electroimmunoassay technique for uromucoid in urine, the excretion of this protein has been studied in normal subjects, calcium stone formers and in patients with chronic renal failure. In the normal subjects there was no significant difference in daily excretion between males and females,