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Urinary Dopamine Metabolites During Cocaine Abstinence

✍ Scribed by Richard Jed Wyatt; Burt Angrist; Farouk Karoum Ph.D.

Book ID
115305001
Publisher
Informa plc
Year
1995
Tongue
English
Weight
692 KB
Volume
4
Category
Article
ISSN
1055-0496

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Basal extracellular dopamine is decrease
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✍ L. H. Parsons; A. D. Smith; Dr. J. B. Justice Jr. πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 743 KB

Rats were treated for 10 days with cocaine (20 mgkg, i.p.1 followed by either 1 or 10 days of abstinence. On the test day a microdialysis method was performed in which dopamine (DA) was added to the perfusate at concentrations above and below the expected extracellular concentration (0,2.5, 5, and 1