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Urinary catecholamines in hyperthermia-related deaths

✍ Scribed by Marja-Leena Kortelainen; Pirkko Huttunen; Tuomo Lapinlampi

Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
533 KB
Volume
48
Category
Article
ISSN
0379-0738

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✦ Synopsis

A group of five hyperthermia-related deaths is presented in which urinary noradrenaline (NA) concentrations were elevated (172.1 +/- 119.4 ng/ml) compared with a control group of rapid violent deaths (43.7 +/- 26.1 ng/ml). Urinary adrenaline (A) concentrations were not elevated in the hyperthermia cases, nor were there any significant differences in urinary dopamine (DA) concentrations between the two groups. All except one of the hyperthermia victims were under the influence of ethanol. It is suggested that a combination of heat stress and ethanol consumption was responsible for the elevated urinary NA in the hyperthermia cases, reflecting increased sympathetic nervous system activity. A combination of high urinary NA with low A seems to be characteristic of hyperthermia fatalities, in contrast to hypothermia deaths, where both NA and A are usually elevated.

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