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Urinary analyte screening: a noninvasive detection method for Down syndrome?

โœ Scribed by Jacob A. Canick; Leonard H. Kellner; Laurence A. Cole; Howard S. Cuckle

Book ID
114382278
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
88 KB
Volume
5
Category
Article
ISSN
1357-4310

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Urinary screening tests for fetal Down syndrome: II. Hyperglycosylated hCG
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Hyperglycosylated hCG is a form of hCG with more complex oligosaccharide side chains. A specific immunoassay was developed to measure hyperglycosylated hCG. Levels were measured in urine samples from 1157 women between 11 to 22 weeks of gestation, undergoing genetic analysis because of advanced mate

Urinary screening tests for fetal Down s
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โœ Laurence A. Cole; Kirsi M. Rinne; Smita M. Mahajan; Utku A. Oz; Shohreh Shahabi; ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 248 KB ๐Ÿ‘ 1 views

Variable results have been reported using urine -core fragment as a marker for fetal Down syndrome. Initial studies by Cuckle et al. (1994) and Canick et al. (1995) indicated that -core fragment was an outstanding marker, detecting >80 per cent of Down syndrome cases. Since these reports, widely var