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Uridine prevents the glucose deprivation-induced death of immunostimulated astrocytes via the action of uridine phosphorylase

โœ Scribed by Ji Woong Choi; Byoung-Kwon Yoo; Chan Young Shin; Mi-Kyoung Ryu; Jong Hoon Ryu; Mahmoud H. el Kouni; Jae-Chul Lee; Won-Ki Kim; Kwang Ho Ko


Book ID
116774808
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
370 KB
Volume
56
Category
Article
ISSN
0168-0102

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Immunostimulated astrocytes become highly vulnerable to glucose deprivation (Choi and Kim: J Neurosci Res 54:870-875, 1998a). The increased vulnerability is caused by the enhanced level of peroxynitrite endogenously produced in glucose-deprived immunostimulated astrocytes. In the present study, we r