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Uridine preserves the expression of respiratory enzyme deficiencies in cultured fibroblasts

✍ Scribed by B. Gérard; T. Bourgeron; D. Chretien; A. Rötig; A. Munnich; P. Rustin

Publisher
Springer
Year
1993
Tongue
English
Weight
126 KB
Volume
152
Category
Article
ISSN
0340-6997

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Pyrimidine excretion by cultured fibrobl
Pyrimidine excretion by cultured fibroblasts: Effect of mutational deficiency in pyrimidine salvage enzymes
✍ Teh-Sheng Chan; Mark Meuth; Howard Green 📂 Article 📅 1974 🏛 John Wiley and Sons 🌐 English ⚖ 340 KB

## Abstract In cultured fibroblasts, a mutation resulting in deficiency of a pyrimidine salvage enzyme leads to excretion of related pyrimidines. For example, absence of thymidine kinase led to loss of thymidine and deoxyuridine, and absence of deoxycytidine kinase to loss of deoxyuridine. Both wil