𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Uric acid infarctions in the kidneys of newborn infants

✍ Scribed by H. Manzke; G. Eigster; D. Harms; K. Dörner; J. Grünitz

Publisher
Springer
Year
1977
Tongue
English
Weight
646 KB
Volume
126
Category
Article
ISSN
0340-6997

No coin nor oath required. For personal study only.

✦ Synopsis

Among 1115 newborns who died during 1957--1976, 136 (12.2%) showed macroscopic renal uric acid infarctions. The incidence depended on the age of the infants and their fluid supply during the first days of life. After introduction of parenteral alkali-glucose infusion in the treatment of perinatal complications, the incidence of renal uric acid infarctions decreased from 19.3% to less than 1.0%. Analysis of the oxypurines in the renal uric acid infarctions of three newborns revealed high percentages of hypoxanthine (31.1%, 21.8% and 11.0%) along with the uric acid. Hypoxanthine ratios above 15% retrospectively point to chronic hypoxia of the newborn.

📜 SIMILAR VOLUMES

Quantitative measurements of the urinary
Quantitative measurements of the urinary excretion of creatinine, uric acid, hypoxanthine and xanthine, uracil, cyclic AMP, and cyclic GMP in healthy newborn infants
✍ H. Manzke; P. Spreter Kreudenstein; K. Dörner; K. Kruse 📂 Article 📅 1980 🏛 Springer 🌐 English ⚖ 504 KB

Serum creatinine, uric acid, and hypoxanthine and xanthine concentrations were determined in 17 mother-infant pairs at the time of delivery. Creatinine and uric acid levels were nearly similar, but hypoxanthine and xanthine were more than twice as high in the blood of the infants than in the blood o