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Uric acid associates with cognition in Parkinson's disease

✍ Scribed by Tua Annanmaki; Anniina Pessala-Driver; Laura Hokkanen; Kari Murros


Book ID
116820430
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
91 KB
Volume
14
Category
Article
ISSN
1353-8020

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Uric acid in Parkinson's disease
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## Abstract Recent studies have provided evidence that uric acid may play a role in the development and progression of Parkinson's disease (PD). Uric acid is a natural antioxidant that may reduce oxidative stress, a mechanism thought to play a role in the pathogenesis of PD. Higher levels of serum

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## Abstract Earlier studies suggest that low plasma uric acid level is a risk factor for Parkinson's disease (PD), and that uric acid associates with iron‐binding proteins. We therefore decided to examine plasma uric acid levels and markers of peripheral iron metabolism in PD patients and healthy c

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## Abstract ## Background Orthostatic hypotension is common in Lewy body disorders and may be related to disease progression and the spread of Lewy body pathology. We therefore hypothesize that PD patients with orthostatic hypotension (OH) have a different cognitive profile compared to PD patients