Urea/Thiourea as Ammonia Surrogate: A Catalyst-Free Synthesis of 2-Substituted 2,3-Dihydroquinazolin-4(1 H )-ones/Quinazoline-4(3 H )-ones
✍ Scribed by Naidu, P. Paradesi; Raghunadh, Akula; Rao, K. Raghavendra; Mekala, Ramamohan; Babu, J. Moses; Rao, B. R.; Siddaiah, V.; Pal, Manojit
- Book ID
- 123619460
- Publisher
- Taylor and Francis Group
- Year
- 2014
- Tongue
- English
- Weight
- 344 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0039-7911
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## Abstract magnified image A general and versatile one‐pot three‐component procedure for the selective synthesis of mono substituted quinazolin‐4(3__H__)‐ones and 2,3‐dihydroquinazolin‐4(1__H__)‐ones were described. The selectivity could be controlled by the ratio of iodine concentration. J. Heter
## Abstract A two‐step sequence involving cyclocondensation of 2‐aminobenzamide with aldehydes and subsequent oxidation by CuCl~2~ gives the required quinazolinones (IV).
## Abstract magnified image A solvent‐ and catalyst‐free one‐pot three‐component condensation reaction approach was developed for the synthesis of a new class of 3‐(2′‐benzothiazolyl)‐2,3‐dihydroquinazolin‐4(1__H__)‐ones in relatively good yields.