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Urea synthesis by perfused rat liver— Studies of CCI4-induced cirrhosis

✍ Scribed by Guido O. Perez; Barbara Rietberg; Barbara Owens; Tally Parker; Hilda Obaya; Eugene R. Schiff

Book ID
115774507
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
448 KB
Volume
28
Category
Article
ISSN
0006-2952

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Hypoxia and CCI4-induced liver injury, but not acidosis, impair metabolism of cysteinyl leukotrienes in perfused rat liver
✍ Matthias Wettstein; Wolfgang Gerok; Prof. Dr. Dieter Häussinger 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 796 KB

Uptake, metabolism and biliary elimination of infused cysteinyl leukotrienes were investigated in single-pass perfused rat liver. Hypoxia did not impair uptake of infused [3H]leukotriene C4, but inhibited biliary excretion of radioactivity by about 50% compared with normoxic control experiments. In