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UREA-RESISTANT NEUTROPHIL ALKALINE PHOSPHATASE IN MOTHERS WITH TRISOMY 21 PREGNANCY

✍ Scribed by Grozdea, J.; Vergnes, H.; Martin, J.


Book ID
122851812
Publisher
The Lancet
Year
1983
Tongue
English
Weight
292 KB
Volume
322
Category
Article
ISSN
0140-6736

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πŸ“œ SIMILAR VOLUMES


Heat resistance, immunological and quant
✍ J. Grozdea; H. Vergnes; A. Brisson-Lougarre; G. Bourrouillou; J. Martin; C. Blum πŸ“‚ Article πŸ“… 1988 πŸ› Springer 🌐 English βš– 375 KB

Neutrophil alkaline phosphatase (NAP) was analysed in 25 pregnant women with trisomy 21 foetuses whose chromosomal aberration was recognized by cytogenetic study after amniocentesis. Enzyme investigation was performed at 20-22 weeks of gestation using cytochemical and biochemical techniques. Twenty-

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Activity levels of total and placental alkaline phosphatase (AP) were determined in maternal serum and neutrophils of normal and Down syndrome pregnancies. The placental iso-enzyme (PAP) was identified by its relative stability to urea and heat. Significant increase in the activity of all iso-enzyme

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✍ J. Grozdea; A. Maret; H. Vergnes; G. Bourrouillou; J. Verdier; J. Martin; R. Sal πŸ“‚ Article πŸ“… 1984 πŸ› Springer 🌐 English βš– 374 KB

A study of karyotypes and neutrophil alkaline phosphatase (NAP) was carried out for 66 parents (33 couples) of trisomy 21 children and for 60 control parents (30 couples). Enzyme activity was determined simultaneously by biochemical and cytochemical techniques. In the mothers of trisomy 21 children