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Urea modulation of β-amyloid fibril growth: Experimental studies and kinetic models

✍ Scribed by Jin Ryoun Kim; Adrian Muresan; Ka Yee C. Lee; Regina M. Murphy

Book ID
119824547
Publisher
Cold Spring Harbor Laboratory Press
Year
2008
Tongue
English
Weight
195 KB
Volume
13
Category
Article
ISSN
0961-8368

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## Abstract Amyloid peptide (Aβ) is the major protein component of plaques found in Alzheimer's disease, and the aggregation of Aβ into oligomeric and fibrillic assemblies has been shown to be an early event of the disease pathway. Visualization of the progressive evolution of nanoscale changes in