Uptake Pathways and Subsequent Intracellular Trafficking in Nonviral Gene Delivery
β Scribed by Khalil, I. A.
- Book ID
- 118136089
- Publisher
- American Society for Pharmacology and Experimental Therapeutics
- Year
- 2006
- Tongue
- English
- Weight
- 359 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0031-6997
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract __The impact of a peptide that contains a nuclear localisation sequence (NLS) on intracellular DNA trafficking was studied. We used the adenoviral core peptide mu and an SV40 NLS peptide to condense plasmid DNA (pDNA) prior to formulation with 3__Ξ²__β[__N__β(__N__β²__, N__β²βdimethylamino
## Abstract ## Background In recent years, Math1 gene therapy was indicated to be the future therapy for deafness in combination with other growth factors. However, Math1 delivery using adenovirusβmediated gene delivery or electroporation was impractical. The contribution of Math1 in the combined