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Uptake of taurine by retina in different species

โœ Scribed by M.S. Starr

Book ID
118864713
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
250 KB
Volume
151
Category
Article
ISSN
0006-8993

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Guanidinoethane sulfonate (GES) markedly decreased 3H-taurine accumulated in the retina by the high-affinity uptake process. The effect of GES was dosedependent. Analysis of the kinetics of GES effect revealed that it is a competitive inhibitor. The uptake of taurine by GES was less affected in rat

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## Abstract Highโ€affinity uptake, potassiumโ€stimulated release and receptor binding of ฮณโ€aminobutyric acid (GABA) and taurine were studied in retinas of rats treated with monosodium glutamate (MSG) or iodoacetateโ€malate (IAM). Such treatments produce a selective damage of the inner retinal layers (