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UPTAKE OF GLUCOSE ANALOGUES BY RAT BRAIN CORTEX SLICES: MEMBRANE TRANSPORT VERSUS METABOLISM OF 2-DEOXY-d-GLUCOSE

✍ Scribed by H. Lund-Andersen; Christel S. Kjeldsen

Book ID
111169742
Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
668 KB
Volume
29
Category
Article
ISSN
0022-3042

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## Abstract D‐[3‐^3^H]‐3‐deoxy‐3‐fluoroglucose was synthesized chemically and shown to be transported into rat brain synaptosomes by a saturable process with a K~m~ 6.2 Γ— 10^βˆ’4^ M and a V~max~ 2.8 nmole Β· mg protein^βˆ’1^. After an initial, rapid period of transport, further uptake of the fluorosugar