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Uptake of d- and l-serine in C6 glioma cells

✍ Scribed by Fumihiko Hayashi; Katsunobu Takahashi; Toru Nishikawa

Book ID: 117475969
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 89 KB
Volume: 239
Category: Article
ISSN: 0304-3940
DOI: 10.1016/s0304-3940(97)00892-6

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## Abstract D‐serine is an endogenous N‐methyl‐D‐aspartate (NMDA) receptor coagonist. It is synthesized from L‐serine by serine racemase (SRR), but many aspects of its metabolism remain unclear, especially in the forebrain, which lacks active D‐amino acid oxidase (DAO), the major D‐serine degradati