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Uptake of 4-borono-2-[18F]fluoro-L-phenylalanine in sporadic and neurofibromatosis 2-related schwannoma and meningioma studied with PET

✍ Scribed by Katja Havu-Aurén; Johanna Kiiski; Kaisa Lehtiö; Olli Eskola; Martti Kulvik; Ville Vuorinen; Vesa Oikonen; Jyrki Vähätalo; Juha Jääskeläinen; Heikki Minn

Publisher
Springer
Year
2006
Tongue
English
Weight
402 KB
Volume
34
Category
Article
ISSN
0340-6997

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Synthesis and radiation dosimetry of 4-borono-2-[18F]fluoro-d,l-phenylalanine: A target compound for PET and boron neutron capture therapy
✍ Kiichi Ishiwata; Tatsuo Ido; Alvaro A. Mejia; Masamitsu Ichihashi; Yutaka Mishim 📂 Article 📅 1991 🏛 Elsevier Science ⚖ 408 KB

The 18F-labeling of 4-borono-D-L-phenylalanine (BPA), a potential target compound for cancer treatment with boron neutron capture therapy, is described. By direct fluorination of BPA with [18F]AcOF or [18F]F2 followed by HPLC separation, 4-borono-2-[18F]fluoro-D,L-phenylalanine was prepared with rad