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Uptake and release protocol for assessing membrane binding and permeation by way of isothermal titration calorimetry

โœ Scribed by Tsamaloukas, Alekos D; Keller, Sandro; Heerklotz, Heiko


Book ID
109946472
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
340 KB
Volume
2
Category
Article
ISSN
1750-2799

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## Abstract Transferrin (TF) is a bilobal transport protein that acquires ferric iron from the diet and holds it tightly within the cleft of each lobe (thereby preventing its hydrolysis). The iron is delivered to actively dividing cells by receptor mediated endocytosis in which diferric TF preferen