Interaction of insulin, glucocorticoids,
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Moira S. Lewitt; Heather Saunders; Robert C. Baxter
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Article
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1996
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John Wiley and Sons
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English
⚖ 894 KB
A sensitive RIA was used to examine regulation of IGFBP-1 in H411E rat hepatoma cells. IGFBP-1 was stimulated up to tenfold by dexamethasone and corticosterone, and this stimulation was abolished by RU486. The effect of dexamethasone increased with time in culture. Phorbol 12-myristate 13-acetate (P