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Uptake and metabolism of Δ1-piperidine-2-carboxylic acid by synaptosomes from rat cerebral cortex

✍ Scribed by Yung-Feng Chang; Ambrose K. Charles

Book ID: 115731000
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 468 KB
Volume: 1238
Category: Article
ISSN: 0005-2736
DOI: 10.1016/0005-2736(95)00092-h

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Glutamate (L-glu) is the most important excitatory neurotransmitter in the mammalian central nervous system. Its action is terminated by transporters located in the plasma membrane of neurons and glial cells, which have a critical role in preventing glutamate excitotoxicity under normal conditions.