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Uptake and intracellular handling of iron from transferrin and iron chelates by mitogen stimulated mouse lymphocytes

✍ Scribed by A. Djeha; J.H. Brock

Book ID
119121501
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
417 KB
Volume
1133
Category
Article
ISSN
0167-4889

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## Abstract The mechanisms of iron (Fe) and transferrin (Tf) uptake by the human melanoma cell line, SK‐MEL‐28, have been investigated using chelators and metabolic probes. These data provide evidence for two saturable processes of Fe uptake from Tf, namely, specific receptor‐mediated endocytosis a