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Upregulation of the GABA-transporter GAT-1 in the spinal cord contributes to pain behaviour in experimental neuropathy

✍ Scribed by Marc A.R.C. Daemen; Govert Hoogland; Jean-Maurice Cijntje; Geert H. Spincemaille

Book ID
116770733
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
284 KB
Volume
444
Category
Article
ISSN
0304-3940

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## Abstract The γ‐aminobutyric acid (GABA) transporters GAT‐1, GAT‐2, GAT‐3, and BGT‐1 have been cloned and identified according to their differential amino acid sequences and pharmacologic properties. In contrast to GAT‐1, ‐2, or ‐3, BGT‐1 is capable of utilizing both GABA and betaine as substrate