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Upregulation of p21WAF1/CIP1 leads to morphologic changes and esterase activity in TPA-mediated differentiation of human prostate cancer cell line TSU-Pr1

โœ Scribed by Sugibayashi, Ryo; Shimizu, Takahisa; Suzuki, Toshihiro; Yamamoto, Naoki; Hamada, Hirofumi; Takeda, Ken


Book ID
110064501
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
228 KB
Volume
20
Category
Article
ISSN
0950-9232

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Grape seed extract upregulates p21 (Cip1
โœ Manjinder Kaur; Alpna Tyagi; Rana P. Singh; Robert A. Sclafani; Rajesh Agarwal; ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 424 KB ๐Ÿ‘ 1 views

## Abstract Abnormalities in cell cycle progression provide unlimited replicative potential to cancer cells, and therefore targeting of key cell cycle regulators could be a sound cancer chemopreventive strategy. Earlier, we found that grape seed extract (GSE) increases Cip/p21 protein level and inh