Upregulation of iron regulatory proteins and divalent metal transporter-1 isoforms in the rat hippocampus after kainate induced neuronal injury

Changes in GABA transporters in the rat

Changes in GABA transporters in the rat hippocampus after kainate-induced neuronal injury: Decrease in GAT-1 and GAT-3 but upregulation of betaine/GABA transporter BGT-1

✍ Xiao-Ming Zhu; Wei-Yi Ong 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 461 KB

## Abstract The γ‐aminobutyric acid (GABA) transporters GAT‐1, GAT‐2, GAT‐3, and BGT‐1 have been cloned and identified according to their differential amino acid sequences and pharmacologic properties. In contrast to GAT‐1, ‐2, or ‐3, BGT‐1 is capable of utilizing both GABA and betaine as substrate