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Upregulation of ICAM-1 expression in bronchial epithelial cells by airway secretions in bronchiectasis

โœ Scribed by Stanley C.H. Chan; Daisy K.Y. Shum; George L. Tipoe; Judith C.W. Mak; Erik T.M. Leung; Mary S.M. Ip

Book ID
116872063
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
397 KB
Volume
102
Category
Article
ISSN
0954-6111

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## Abstract Mucus hypersecretion is an important characteristic feature of the pathogenesis of allergy. Although interleukin (IL)โ€4 is known to be an inflammatory mediator in respiratory diseases, the mechanism by which ILโ€4 induces __MUC5AC__ gene expression has not been fully explored. The aim of