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Upregulation of DNA repair genes in active cirrhosis associated with hepatocellular carcinoma

✍ Scribed by Pierre Zindy; Lise Andrieux; Dominique Bonnier; Orlando Musso; Sophie Langouët; Jean Pierre Campion; Bruno Turlin; Bruno Clément; Nathalie Théret

Book ID
116464968
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
321 KB
Volume
579
Category
Article
ISSN
0014-5793

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## Abstract CpG island methylator phenotype (CIMP) involves the targeting of multiple genes by promoter hypermethylation. Telomerase plays an important role in the development of cellular immortality and oncogenesis. To gain insight into the role of epigenetic aberration of telomerase‐related genes