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Upregulation of Bradykinin B2 Receptor Expression by Neurotrophic Factors and Nerve Injury in Mouse Sensory Neurons

โœ Scribed by Yih-Jing Lee; Olof Zachrisson; David A. Tonge; Peter A. McNaughton


Book ID
115637817
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
345 KB
Volume
19
Category
Article
ISSN
1044-7431

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## Abstract Rat1 fibroblasts stably transfected with the rat angiotensin II (AngII) AT1a and bradykinin (BK) B2 receptor cDNAs gained the ability to bind Ang II and BK. Wildโ€type Rat1 cells bound neither ligand. Exposure to either effector led to characteristic Gฮฑi and Gฮฑq signal cascades, the rele