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Update on the role of Toll-like receptors during bacterial infections and sepsis

✍ Scribed by Sylvia Knapp

Publisher: Springer Vienna
Year: 2010
Tongue: German
Weight: 101 KB
Volume: 160
Category: Article
ISSN: 0043-5341
DOI: 10.1007/s10354-010-0765-6

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## Abstract Microglia are activated by lipopolysaccharide (LPS) to produce neurotoxic pro‐inflammatory factors and reactive oxygen species (ROS). While a multitude of LPS receptors and corresponding pathways have been identified, the detailed mechanisms mediating the microglial response to LPS are