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Update on gene and stem cell therapy approaches for spinal muscular atrophy

✍ Scribed by Donnelly, Eleanor M; Boulis, Nicholas M

Book ID
120984685
Publisher
Informa plc
Year
2012
Tongue
English
Weight
298 KB
Volume
12
Category
Article
ISSN
5847-4714

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Human hereditary neurodegenerative diseases are genetically and mechanistically very heterogeneous and so are spinal muscular atrophies and cerebellar ataxias in the mouse, despite the common phenomenon of neuronal death. In this species, a number of mutations impair spermiogenesis in addition to ne