## Abstract Denosumab, a fully human monoclonal antibody to RANKL, decreases bone remodeling, increases bone density, and reduces fracture risk. This study evaluates the time course and determinants of bone turnover marker (BTM) response during denosumab treatment, the percentage of denosumab‐treat
✦ LIBER ✦
Update on denosumab in postmenopausal osteoporosis—recent clinical data
✍ Scribed by Christian Muschitz MD, Astrid Fahrleitner-Pammer MD, Johannes Huber MD, PhD, Elisabeth Preisinger MD, Stefan Kudlacek MD, Heinrich Resch MD
- Book ID
- 118793812
- Publisher
- Springer Vienna
- Year
- 2012
- Tongue
- German
- Weight
- 880 KB
- Volume
- 162
- Category
- Article
- ISSN
- 0043-5341
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## Abstract Denosumab reduces the risk of new vertebral and nonvertebral fractures. Previous trials suggest that the efficacy of antiresorptives on fractures might differ by patients' characteristics, such as age, bone mineral density (BMD), and fracture history. In the FREEDOM study, 7808 women ag