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Up-regulation ofNEK2byMicroRNA-128Methylation is Associated with Poor Prognosis in Colorectal Cancer

✍ Scribed by Takahashi, Yusuke; Iwaya, Takeshi; Sawada, Genta; Kurashige, Junji; Matsumura, Tae; Uchi, Ryutaro; Ueo, Hiroki; Takano, Yuki; Eguchi, Hidetoshi; Sudo, Tomoya; Sugimachi, Keishi; Yamamoto, Hirofumi; Doki, Yuichiro; Mori, Masaki; Mimori, Koshi

Book ID: 121848875
Publisher: Springer
Year: 2013
Tongue: English
Weight: 489 KB
Volume: 21
Category: Article
ISSN: 1068-9265
DOI: 10.1245/s10434-013-3264-3

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## Abstract Genomic alterations play important roles in colorectal cancer (CRC) carcinogenesis. Here, we aimed to identify and characterize recurrent copy‐number alterations (CNAs) associated with clinical outcome of CRC by the use of single nucleotide polymorphism arrays, genomic quantitative PCR