Up-regulation of ZO-1 expression and barrier function in cultured human corneal epithelial cells by substance P
β Scribed by Ji-Ae Ko; Ryoji Yanai; Teruo Nishida
- Book ID
- 113621385
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 715 KB
- Volume
- 583
- Category
- Article
- ISSN
- 0014-5793
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## Abstract The formation of a barrier by tight junctions is important in epithelia of various tissues. Substance P (SP) and insulinβlike growth factor (IGF)β1 synergistically promote barrier function in the corneal epithelium. We have now examined the effects of SP and IGFβ1 on expression of the t
## Abstract Interactions between epithelial cells and fibroblasts play important roles in tissue homeostasis. With the use of a coculture system in which human corneal fibroblasts and epithelial cells are cultured on opposite sides of a collagen (vitrigel) membrane, we have examined the effects of