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Up-regulation of Syk Activity during HL60 Cell Differentiation into Granulocyte but Not into Monocyte/Macrophage-Lineage

✍ Scribed by Suofu Qin; Hirohei Yamamura


Book ID
115580613
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
460 KB
Volume
236
Category
Article
ISSN
0006-291X

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Inhibition of p38MAP kinase potentiates
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## Abstract Monocytic differentiation of HL60 cells induced by 1,25‐dihydroxyvitamin D~3~ (1,25 D~3~) has been recently shown (Exp Cell Res 258, 425, 2000) to be enhanced by an exposure to SB203580 or to SB202190, specific inhibitors of p38MAP kinase, with concomitant up‐regulation of the c‐jun N t